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Ming-Shi Chang Selected Research

interleukin 20 (IL-20)

12/2021IL-20 is involved in obesity by modulation of adipogenesis and macrophage dysregulation.
2/2021Anti-IL-20 Antibody Protects against Ischemia/Reperfusion-Impaired Myocardial Function through Modulation of Oxidative Injuries, Inflammation and Cardiac Remodeling.
2/2021Interleukin-24 protects against liver injury in mouse models.
5/2020Anti-IL-20 antibody improved motor function and reduced glial scar formation after traumatic spinal cord injury in rats.
1/2020IL-20 antagonist suppresses PD-L1 expression and prolongs survival in pancreatic cancer models.
1/2020IL-20 promotes hypoxia/reoxygenation-induced mitochondrial dysfunction and apoptosis in cardiomyocytes by upregulating oxidative stress by activating the PKC/NADPH oxidase pathway.
1/2020Targeting interleukin-20 alleviates paclitaxel-induced peripheral neuropathy.
11/2018The role of IL-20 in chronic kidney disease and diabetic nephropathy: Pathogenic and therapeutic implications.
4/2018IL-20 bone diseases involvement and therapeutic target potential.
12/2017Anti-IL-20 monoclonal antibody inhibited tumor growth in hepatocellular carcinoma.
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Ming-Shi Chang Research Topics

Disease

14Rheumatoid Arthritis
12/2017 - 10/2002
11Neoplasms (Cancer)
01/2020 - 06/2006
11Atherosclerosis
11/2018 - 09/2006
11Psoriasis (Pustulosis Palmaris et Plantaris)
11/2018 - 10/2002
10Inflammation (Inflammations)
12/2021 - 12/2004
5Fibrosis (Cirrhosis)
02/2021 - 09/2008
5Osteoporosis
04/2018 - 08/2011
5Breast Neoplasms (Breast Cancer)
01/2015 - 02/2012
4Osteolysis
04/2018 - 02/2012
4Arthritis (Polyarthritis)
01/2014 - 09/2006
3Hypoxia (Hypoxemia)
02/2021 - 04/2009
3Liver Cirrhosis (Hepatic Cirrhosis)
02/2021 - 09/2014
3Asthma (Bronchial Asthma)
01/2019 - 12/2004
3Hepatocellular Carcinoma (Hepatoma)
12/2017 - 04/2003
3Stroke (Strokes)
09/2014 - 08/2011
3Melanoma (Melanoma, Malignant)
09/2005 - 10/2002
2Body Weight (Weight, Body)
12/2021 - 09/2015
2Ischemia
01/2020 - 04/2009
2Diabetic Nephropathies (Diabetic Nephropathy)
11/2018 - 01/2017
2Bone Fractures (Bone Fracture)
04/2018 - 04/2016
2Metabolic Bone Diseases (Osteopenia)
04/2016 - 08/2011
2Shock
01/2013 - 01/2008
2Ductal Carcinoma
02/2012 - 02/2012
2Autoimmune Diseases (Autoimmune Disease)
06/2006 - 10/2002
1Insulin Resistance
12/2021
1Obesity
12/2021
1Gliosis
05/2020
1Mitochondrial Diseases (Mitochondrial Disease)
01/2020
1Peripheral Nervous System Diseases (PNS Diseases)
01/2020
1Neuroinflammatory Diseases
01/2020
1Pancreatic Neoplasms (Pancreatic Cancer)
01/2020
1Pneumonia (Pneumonitis)
01/2019
1Respiratory Hypersensitivity
01/2019
1Chronic Renal Insufficiency
11/2018
1Diabetes Complications
11/2018
1Renal Insufficiency (Renal Failure)
11/2018
1Bone Diseases (Bone Disease)
04/2018
1Liver Neoplasms (Liver Cancer)
04/2018
1Osteoarthritis
01/2017
1Diabetes Mellitus
01/2017
1Chronic Kidney Failure (Chronic Renal Failure)
01/2017
1Prostatic Neoplasms (Prostate Cancer)
01/2015
1Wounds and Injuries (Trauma)
06/2013
1Esophageal Squamous Cell Carcinoma
01/2013
1Esophageal Neoplasms (Esophageal Cancer)
01/2013
1Uremia
01/2013
1Reperfusion Injury
01/2013
1Mouth Neoplasms (Oral Cancer)
11/2012
1Neoplasm Metastasis (Metastasis)
02/2012
1Brain Infarction
04/2009

Drug/Important Bio-Agent (IBA)

32interleukin 20 (IL-20)IBA
12/2021 - 10/2002
24CytokinesIBA
05/2020 - 04/2003
14Interleukin-10 (Interleukin 10)IBA
01/2017 - 10/2002
11Monoclonal AntibodiesIBA
04/2018 - 08/2011
10InterleukinsIBA
02/2021 - 09/2005
5Interleukin-6 (Interleukin 6)IBA
03/2012 - 06/2006
4Interleukin-22 (IL-22)IBA
06/2006 - 10/2002
2AllergensIBA
01/2019 - 12/2004
2Cathepsin GIBA
01/2015 - 02/2012
2Cathepsin KIBA
01/2015 - 02/2012
2Fibronectins (Fibronectin)IBA
01/2015 - 02/2012
2AntibodiesIBA
09/2014 - 09/2005
2Biological ProductsIBA
01/2013 - 09/2005
2Matrix Metalloproteinases (MMPs)IBA
02/2012 - 11/2010
2EnzymesIBA
11/2010 - 09/2005
2ImmunosorbentsIBA
11/2010 - 09/2005
2DNA (Deoxyribonucleic Acid)IBA
01/2008 - 09/2006
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
08/2007 - 06/2006
2ApolipoproteinsIBA
09/2006 - 06/2002
1LeptinIBA
12/2021
1Netrin ReceptorsIBA
12/2021
1Glucose (Dextrose)FDA LinkGeneric
12/2021
1Netrin-1IBA
12/2021
1Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA
12/2021
1Oxidoreductases (Dehydrogenase)IBA
02/2021
1NADP (NADPH)IBA
02/2021
1AntioxidantsIBA
02/2021
1interleukin-24 (ST16)IBA
02/2021
1NADPH Oxidases (NAD(P)H oxidase)IBA
01/2020
1Paclitaxel (Taxol)FDA LinkGeneric
01/2020
1OvalbuminIBA
01/2019
1Cyclin D1IBA
12/2017
1Blood Glucose (Blood Sugar)IBA
01/2017
1Estrogens (Estrogen)FDA Link
09/2015
1VimentinIBA
01/2015
1Cadherins (E-Cadherin)IBA
01/2015
1Metalloproteases (Metalloproteinases)IBA
09/2014
1salicylhydroxamic acid (SHAM)IBA
01/2013
1Pharmaceutical PreparationsIBA
01/2013
1Immunoglobulin G (IgG)IBA
01/2013
1Cyclin B1IBA
01/2013
1Reactive Oxygen Species (Oxygen Radicals)IBA
11/2012
1Matrix Metalloproteinase 9 (Gelatinase B)IBA
02/2012
1ChemokinesIBA
02/2012
1Etanercept (Enbrel)FDA Link
11/2010
1cobaltous chloride (cobalt(II)chloride)IBA
04/2009
1LuciferasesIBA
04/2009

Therapy/Procedure

2Ovariectomy (Oophorectomy)
04/2018 - 09/2015
2Therapeutics
01/2013 - 10/2002
1Drug Therapy (Chemotherapy)
01/2020